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Well designed operational research is needed to refine
2019-05-17
Well designed operational research is needed to refine this starting point. Research is also needed to find out whether prophylactic valganciclovir treatment in high-risk patients might reduce AIDS mortality as well as blindness, as substantial data suggest. WHO leadership is needed to provide cytom
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This study provides an innovative model
2019-05-17
This study provides an innovative model to harness national household survey data to quantify the effects of the various malaria control interventions. The model accounts for the spatial dependence in parasitaemia as a consequence of the heterogeneous distribution of malaria transmission and its dri
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Bone marrow resident Macs Osteomacs are located in canopy li
2019-05-16
Bone marrow resident Macs (Osteomacs) are located in canopy-like structures in endosteal and periosteal surfaces, above osteoblasts [6]; osteoclasts result from the fusion of several myeloid osteoclast precursors [7]. Osteomacs constitute approximately 17% of the bone marrow LY2109761 manufacturer
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According to the labeling of dabigatran in Japan patients to
2019-05-16
According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage
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A decreasing trend in CRT D implantation has been
2019-05-16
A decreasing trend in CRT-D implantation has been reported recently, based on the database from the National Inpatient Sample in the USA [20]. They found that advancing age and an increasing comorbidity burden were associated with a reduced likelihood of CRT-D, and speculated that the decline in CRT
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Surgery especially modified radical mastectomy is the gold
2019-05-16
Surgery, especially modified radical mastectomy, is the “gold standard” for the treatment of male breast cancer. Postoperative adjuvant radiotherapy is recommended for male patients with large breast cancer and axillary lymph node and chest muscle involvement; it can reduce the risk of local cancer
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br Growth supportive characteristics of the BM vascular nich
2019-05-16
Growth-supportive characteristics of the BM vascular niche Similar to normal tissues, tumours also need functional blood vessels to support their growth via the delivery of oxygen and nutrients. When a DTC starts proliferating into a micrometastasis, it drives angiogenesis to build new blood vess
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ER provides the clinician with a rapid and
2019-05-16
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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br El fuego como fuerza destructora
2019-05-16
El fuego como fuerza destructora endógena Según Elizabeth Monasterios Pérez, la poesía de Pacheco, al igual que la de Octavio Paz, por ejemplo, se nutre de cosmología prehispánica. Con todo, prosigue Monasterios Pérez, Pacheco se demarca de Paz mediante la configuración de un “principio apocalípt
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Adem s de favorecer la configuraci n del capital
2019-05-15
Además de favorecer la configuración del capital literario, la crítica encarna un momento esencial, el último, del proceso de producción de la obra literaria (Bourdieu: 258); por su parte, Owen no solo funge de intermediario en esta “historia de las rivalidades” como crítico, sino que forma parte de
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One of the lessons the
2019-05-15
One of the lessons the global health cisapride learned from its experience with HIV was the need to rapidly identify individuals who are eligible for treatment. Yet HCV is severely underdiagnosed ( Lancet Glob Health —The following sentence should have read “Alarmingly, almost half of both for ch
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Finally it is highly interesting to note that
2019-05-15
Finally, it is highly interesting to note that human endogenous retroviruses have been suggested to play a role in the etiology of both MS and MPN [7,9]. Supporting this notion, both MS and MPN are treated with type 1 interferons, which have very potent antiviral and immunomodulating effects. Indeed
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nuciferine br Future potential cardiac examinations for long
2019-05-15
Future potential cardiac examinations for long-duration spaceflights Currently available treatments for emergency cases in spaceflight Astronaut Crew Medical Officers (CMO) aboard the ISS receive 40–70h of medical training, including CPR training, within 18 months preceding their mission (Fig.
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Catheter ablation was performed from the
2019-05-15
Catheter ablation was performed from the basal septum to the apex in the sites where the right bundle branch potential could be recorded. Radiofrequency (RF) ezh2 inhibitor was delivered with a temperature controlled 4-mm-tip deflectable catheter (Biosense Webster, Diamond Bar, CA, USA) with a targ
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br Introduction Patients with advanced
2019-05-15
Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly
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