• Both NHEJ and HDR have been used in hPSCs for

  2018-11-09

  

  Both NHEJ and HDR have been used in hPSCs for gene editing (Byrne et al., 2015; Chen et al., 2014b; Ding et al., 2013a; Ding et al., 2013b; Genga et al., 2015; Hockemeyer et al., 2011; Hou et al., 2013; Kleinstiver et al., 2016; Slaymaker et al., 2016). For targeted gene knockout in hPSCs, NHEJ usua

• The shape and the location of this

  2018-11-09

  

  The shape and the location of this peak were examined, and the parameters necessary for constructing the Fano profile (6) were computed (see Table 2). The computed peak location is in good agreement with the experiment; unfortunately, however, since it is narrow and highly intense, no specific conc

• More importantly as social and family structures have change

  2018-11-09

  

  More importantly, as social and family structures have changed rapidly, the living arrangements of older people are perceived as a dynamic process rather than a static status, which in turn may influence the adaptability to new circumstances, and thereby upon older people\'s mortality (Li and Li, 20

• In the East Pacific Ocean conditions were perfect

  2018-11-09

  

  In the East Pacific Ocean, conditions were perfect for concentration of Mo. Oceanic crust that formed during the period from Jurassic to Cretaceous, and even Cenozoic, was subducted, carrying with it Mo-rich sediments formed during the OAEs (Fig. 3). Some of the sediments may have been scraped off t

• br Materials and Methods br

  2018-11-09

  

  Materials and Methods Results Discussion Previous studies have indicated that irisin could improve dyslipidemia and hepatic steatosis in mice (Xiong et al., 2015). The decrement of lipid accumulation in hepatocytes was proposed to result mainly from the suppression of triglyceride synthesis

• br Introduction Learning the relationship between threatenin

  2018-11-09

  

  Introduction Learning the relationship between threatening events and the cues that predict the onset of those events is an adaptive process that allows an individual to anticipate and minimize exposure to danger (Ohman and Mineka, 2001). Failure to regulate fear purchase EZ Cap Reagent AG (3\' O

• In early and mid adolescence peer relationships

  2018-11-09

  

  In early- and mid-adolescence, peer relationships are particularly salient: individuals show an increased sensitivity to acceptance and rejection by peers (Brown, 2004; Nelson et al., 2005; Sebastian et al., 2010a), and an increase in awareness of others’ opinions (Parker et al., 2006; Vartanian, 20

• Another factor in all of

  2018-11-09

  

  (5) Another factor in all of these disorders is the level of frontal lobe blood flow. Decreased frontal lobe blood flow, or hypofrontality, is present in a number of disorders, e.g. insomnia, schizophrenia, bipolar disorder, to some extent. Such a state during waking would lead to reflexive reaction

• br Experimental work and modeling br

  2018-11-09

  

  Experimental work and modeling Results and discussion Discussion and conclusions It is very important to determine which type of cell lines is suitable as sensorial component of the ECIS sensor. In addition to sensitivity to toxicants, the ECIS sensors require adherent harmine hydrochloride

• In our opinion the idea of planning

  2018-11-09

  

  In our opinion, the idea of planning does not involve whether socialism is as good or as bad as capitalism. Social production and consumption as well as planning were key for Marx, as expressed in the Grundrisse (Marx, 1973, 108 and 109): So, in a socialist economy planning must be possible and its

• By sorting and sequencing HBsAg memory and PC cells we

  2018-11-09

  

  By sorting and sequencing HBsAg+(memory) and PC+ cells, we were able to confirm that crm1 specific to the vaccine caused the signatures we saw in the repertoire. Both the HBsAg+ and PC+ clusters had increased convergence, mutation, and size compared to the total repertoire, and tracking the kinetics

• brain metabolism br Materials and methods br

  2018-11-08

  

  Materials and methods Results and discussions Conclusion The capability of the CTs extracts to scavenge free radicals in different systems, indicating that they may be useful therapeutic agents for treating various chronic diseases which are more related to oxidative stress associated disea

• OCN is a marker of late stage osteogenic

  2018-11-08

  

  OCN is a marker of late stage osteogenic differentiation and regulates matrix mineralization during bone formation. VitD3 had the greatest positive effect on this transcript while Dex had the greatest negative effect. This effect has previously been documented for VitD3 supplemented osteoblast cultu

• It is evident that within our

  2018-11-08

  

  It is evident that within our model, compressed collagen gels play a key role in driving limbal stem cell growth and phenotype. Our results suggest that these changes are due to the increased mechanical properties of compressed collagen gels with improved surface nanostructure. More importantly LEC

• TRPM channel has been implicated in

  2018-11-08

  

  TRPM7 channel has been implicated in cell survival and proliferation. In zebra fish, TRPM7 knockouts showed several development defects in skeletal muscle and growth retardation (Elizondo et al., 2005). TRPM7 was also reported to regulate cell migration (Wei et al., 2009). Knocking down TRPM7 in DT

15771 records 1033/1052 page Previous Next First page 上5页 10311032103310341035 下5页 Last page