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Recently a method for in vivo photoactivation of
2020-11-18
Recently, a method for in vivo photoactivation of MDV 3100 expressing PA-GFP in precise microanatomical compartments was described (Victora et al., 2010), which makes it possible to optically mark Tfh cells and track them 20 hr later (Shulman et al., 2013). Unexpectedly, it was reported that Tfh ce
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The majority of APC C subunits form a giant
2020-11-18
The majority of APC/C subunits form a giant scaffold, which was originally named the arc lamp, based on its shape when viewing APC/C from one side (Figure 1 and Box 1) [24]. The scaffold consists of two modules: the TPR lobe resembles the curved post and lamp, and the platform resembles the ZJ 43 s
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br Materials and methods br Discussion To date only a
2020-11-18
Materials and methods Discussion To date, only a fraction of studies pertaining to analysis of avian semen have focused on the study of DNA, with the vast majority being associated with the effects of cryopreservation on sperm DNA integrity (Kotłowska et al., 2007, Madeddu et al., 2009, Partyk
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A set of small molecule LigI inhibitors were identified thro
2020-11-18
A set of small molecule LigI inhibitors were identified through an in silico structure-based screen, using the atomic resolution structure of LigI complexed with nicked DNA [[18], [26]]. This screen yielded inhibitors that were selective for LigI (L82), inhibited both LigI and LigIII (L67) and inhi
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In summary these results are consistent with
2020-11-18
In summary, these results are consistent with our hypothesis that chemical nitrosation of BMAA to N-BMAA results in the formation of an alkylating agent. Furthermore, we have shown that N-BMAA is more toxic than BMAA itself. Previously, methylazoxymethanol (MAM), which is also present in the cycad n
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SYBR Safe DNA Gel Stain receptor br Results br Discussion In
2020-11-18
Results Discussion In addition to contributing to amino SYBR Safe DNA Gel Stain receptor and lipid biosynthesis, mitochondrial metabolism affects nucleotide biosynthesis. Indeed, many components that contribute to both pyrimidine and purine bases are derived directly or indirectly from mitoch
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scopolamine hydrobromide With regard to the DGATs we have
2020-11-17
With regard to the DGATs, we have found that the majority of algal species encode at least one DGAT1, although it appears to be absent from Ostreococcus and Micromonas, as is the case for yeast, S. cerevisiae. More surprising is the presence of multiple DGAT2 genes in algae, with the exception of C.
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In the pleural exudates which reflect the in
2020-11-17
In the pleural exudates, which reflect the in vivo conditions, the concentrations of CysLTs and PGE2 were quite similar. However, when cancer CT-99021 were cultured for 24 h, both analyses of cell culture medium and cell incubations with Ca2+ ionophore showed low levels of CysLTs. In contrast, the
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Stressful life events are modulators of mood and can
2020-11-17
Stressful life events are modulators of mood and can trigger a variety of destructive behavior, including drug abuse and relapse in addicts (Association, 2013; Chen et al., 2012; Sinha, 2009). Likewise, drug-associated stimuli evoke a negative affective state in abstinent drug users. Compelling evid
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As mentioned above of various constitutive models the
2020-11-17
As mentioned above, of various constitutive models, the Chaboche kinematic model was widely used [3,7,[23], [24], [25], [26], [27]]. There exist many significant literature around the Chaboche/Chaboche type plasticity model calibration and its parameter determination methods. Aguis et al. [28] emplo
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Endothelial dysfunction has been associated with
2020-11-17
Endothelial dysfunction has been associated with most of the established cardiovascular risk factors, such as hypercholesterolemia, hypertension, smoking, diabetes mellitus, a positive history of premature CAD and elevated SB 290157 trifluoroacetate salt receptor homocysteine 4, 26, 27. Endothelial
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RHA is an agricultural by product
2020-11-17
RHA is an agricultural by-product obtained from the burning process of rice hull [7], [8]. Rice hull is the outer layer of paddy grain. About 20% of rice hull converts into RHA when it is burnt during the glycerophosphate generation processes [8], [9]. If RHA produced at less than 700 °C, it chemic
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br Disclosure statement br Acknowledgment This work was
2020-11-17
Disclosure statement Acknowledgment This work was supported by the National Natural Science Foundation of China (81270704, 81330018). Background Over-expression of cyclooxygenase-2 (COX-2) is common in many malignancies including non-small cell lung cancer (NSCLC) and is associated with po
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br Methods br Results br Discussion I R induces
2020-11-17
Methods Results Discussion I/R induces oxidative stress and increases the intracellular levels of ROS, resulting in tissue damage [31]. ROS is generated by mitochondrial electron transport chain, nicotinamide Deoxycholic acid dinucleotide phosphate (NADPH) oxidase complex, xanthine oxidase
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Glycolysis is important to maintain the vital functions of T
2020-11-17
Glycolysis is important to maintain the vital functions of T. gondi. Extracellular T. gondii shift its Berberine hydrochloride metabolism towards glycolysis, based on the observation that a relocation of glycolytic enzymes from the cytosol to the pellicle occurs at the time when tachyzoites egress
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