• In this issue of Mark Nicol

  2019-06-15

  

  In this issue of , Mark Nicol and colleagues report the diagnostic accuracy of two commercially available rapid urine tests to identify active tuberculosis in children. Lipoarabinomannan is a unique component of the mycobacterial nisoldipine that is excreted in the urine of some patients with tuberc

• br We appreciate the response by Sharath

  2019-06-15

  

  We appreciate the response by Sharath Nagaraja and Ritesh Menezes to our Comment, in which we had argued that patients with tuberculosis deserve a complete and patient-centric solution, irrespective of whether they seek care in the public or private health sector. Nagaraja and Menezes seem to have

• IRF expression had previously been described

  2019-06-15

  

  IRF1 expression had previously been described as a factor that contributes to susceptibility for HIV-1 infection [14]. Our findings evidenced a different expression modulation of this transcription factor in the two groups of DC according with the expression of the important Th1 driving cytokine IL-

• Numerous clinical trials phase II and phase III have

  2019-06-15

  

  Numerous clinical trials (phase II and phase III) have been then designed to evaluate the efficacy of denosumab in oncology mainly in breast and prostate bone metastases (Table 1). These studies revealed that denosumab reduced significantly bone turnover markers similarly to osteoporotic patients. M

• De manera concomitante la confecci n de relaciones

  2019-06-15

  

  De manera concomitante, la confección de relaciones y crónicas devino una forma de obtener recompensas o beneficios del favor real. De este modo, tanto particulares como miembros de corporaciones (v. gr. la iglesia) elaboraron sus historias (manuscritas o impresas) y buscaron hacerlas llegar al mona

• No livro de fato a aproxima o aparece

  2019-06-14

  

  No livro, de fato, INK 128 aproximação aparece muito mais como uma metáfora do que como um tratado. Tudo parece girar em torno da palavra intuição ou de uma ideia de sensação. Algo a ver com o inexplicável. “ por que, ao entrar no quarto onde esse homem passa seus dias recluso [o homem imóvel], algu

• The imbalances in the current R D

  2019-06-14

  

  The imbalances in the current R&D system were the subject of the 2012 report of WHO\'s Consultative Expert Working Group on Research and Development (CEWG). The CEWG recommended a global binding agreement that provides a needs-driven and evidence-based framework for R&D, guided by the core principle

• br Case report A year old man

  2019-06-14

  

  Case report A 68-year-old man with dilated cardiomyopathy [Left ventricular (LV) ejection fraction, 15%] of unknown etiology and nonsustained ventricular tachycardia was referred to our institution. He was prescribed a β-blocker (2.5mg of carvedilol, which was gradually increased to 20mg) and 200

• br What is the best pacing algorithm for vasovagal syncope

  2019-06-14

  

  What is the best pacing algorithm for vasovagal syncope? Conclusions Conflict of interest Introduction The number of implantations of cardiovascular implantable electronic devices (CIEDs), including permanent pacemakers (PPMs), implantable cardioverter defibrillators (ICDs), and cardiac

• Fig shows different PVCs observed

  2019-06-14

  

  Fig. 4 shows 2 different PVCs observed before (PVC 1) and after the application of radiofrequency gssg (PVC 2) in patient 17. After ablation of PVC 1, a different PVC (PVC 2) with a slightly different QRS morphology from that of PVC 1 was observed. Fig. 5 shows the activation sequence of PVC 1 and t

• It is in this context that the

  2019-06-14

  

  It is in this context, that the recent study of Matsuyama et al. sheds further light on the relationships between histoanatomy and atrial arrhythmogenesis . This investigation used high-density optical mapping to study atrial flutter/atrial fibrillation in isolated rat hearts . Atrial arrhythmia was

• br Practical management of perioperative anticoagulation and

  2019-06-14

  

  Practical management of perioperative anticoagulation and antiplatelet therapy in CIED surgery By integrating the current literature and the experience from our own practice, we developed a practical algorithm recently to guide the perioperative management of anticoagulation and antiplatelet ther

• DAPTinhibitor Desde ese ngulo es visible c mo la Antig

  2019-06-14

  

  Desde ese ángulo es visible cómo la Antigüedad vivía en la medida que era apropiada por los criollos: la gramática latina de Andrés Bello fue novedosa en cuanto explicó la lengua desde el castellano actual (y americano), con la conciencia que éste tenía una estructura distinta. Los símbolos grecorro

• br Discussion The natural history of PMF is characterized by

  2019-06-14

  

  Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable

• br As outlined in in October my vision for WHO

  2019-06-13

  

  As outlined in in October, 2016, my vision for WHO can be summed up in five words: equity, rights, responsiveness, evidence, and partnership. In this nrf2 activator context, I am pleased to respond to the authors of the open letter in , on the leadership role that WHO must play in tackling the hig

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