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The aim of this study was to determine the therapeutic
2019-05-24

The aim of this study was to determine the therapeutic relevance of blocking RANKL in Ewing\'s sarcoma by using OPG administered by non-viral gene transfer approaches in two models of human Ewing sarcoma in immunodeficient mice. OPG was administered using amphiphilic polymers constituted by blocks o
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Preference for injectable therapy over oral therapy contrary
2019-05-24

Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne
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AC regimens have also demonstrated better preventive effects
2019-05-24

AC regimens have also demonstrated better preventive effects in terms of stroke than AP regimens [18–20], whereas major or minor bleeding events in Japanese patients with cardiovascular diseases were reported to be more frequent in patients taking AC than in those taking AP regimens [21]. To underst
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br Hasta donde yo s ese texto que
2019-05-24

Hasta donde yo sé, ese texto, que es una carta abierta “Au journal La Réforme”, es el único en La Tribune des Peuples que aparece firmado con el nombre de Bilbao. De ello se podría deducir que el joven exiliado chileno habría tenido un papel marginal en la empresa comandada por Mickiewicz. Pero el
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Givinostat Polysaccharides fatty acid esters glycosides
2019-05-24

Polysaccharides, fatty Givinostat esters, glycosides, iridoids, anthraquinones, flavonoids, phytosterols, carotenoids, vitamin A, antraquinones, potassium, and others have been identified as putative active ingredients in NJ. Our previous report indicated that gentisic, p-hydroxybenoic, and chloroge
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According to the labeling of dabigatran
2019-05-24

According to the labeling of dabigatran in Japan, patients to be considered for the prescription of the lower dose of 220mg/day are as follows: (1) aged ≥70 years, (2) with moderate renal impairment (ClCr 30–50mL/min), (3) concomitant use of a p-glycoprotein inhibitor, and (4) history of hemorrhage
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Landiolol is an ultra short acting superselective titration
2019-05-24

Landiolol is an ultra-short-acting, β1-superselective, titration intravenous β-adrenergic blocker that is rapidly metabolized to inactive forms, and has relatively smaller negative inotropic effects on the cardiac output [11]. Landiolol is more effective for controlling rapid CM-272 rate than digox
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CLL associated HLH was first documented in the
2019-05-24

CLL associated HLH was first documented in the form of a case series report which included six patients treated for CLL who subsequently developed the phagocytic syndrome months to years later.[7] As these cases occurred prior to publication of the 1991 HLH diagnostic guidelines, the authors postula
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An imperative need now exists for new thinking
2019-05-24

An imperative need now exists for new thinking, increased resources, and better training of health-care staff working with these new populations. At a time when there is a danger of religiopolitical extremism in the wake of perceived (and sometimes real) antipathy to newcomers, the health sector has
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br Risk of bleeding complications
2019-05-23

Risk of bleeding complications with dual antiplatelet agents Dual antiplatelet therapy (DAPT) with combined aspirin and clopidogrel has become a standard treatment after percutaneous coronary intervention (PCI). Recent studies have examined the impact of such therapy on the incidence of bleeding
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In the present study the timing of the
2019-05-23

In the present study, the timing of the LA potentials in respect to the timing of the CSM potentials depended closely on the direction of impulse propagation across the interatrial connection at the proximal CS. Thus, a LA → CSM activation sequence was observed only when the wavefront traveled throu
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En estos trabajos la referencia a la obra de Ernesto
2019-05-23

En estos trabajos la referencia Tasquinimod la obra de Ernesto Laclau es una constante, que a su vez es marginal. Casi todos los estudios lo citan como un antecedente en ese lugar común que se transformó el referir a la polisemia del concepto y es difícil considerar un estado de la cuestión sin su i
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Y no se trata s lo de observar estas pr
2019-05-23

Y no se trata sólo de observar estas prácticas de manera amplia, general y tersa, sino que también es posible intentar reconstruir las experiencias estéticas y los espacios de disputa simbólica que cada una de ellas puede llegar Amyloid β-Peptide (1-42) encerrar, en nueva proliferación de espacios d
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flap inhibitor br As outlined in in October
2019-05-23

As outlined in in October, 2016, my vision for WHO can be summed up in five words: equity, rights, responsiveness, evidence, and partnership. In this flap inhibitor context, I am pleased to respond to the authors of the open letter in , on the leadership role that WHO must play in tackling the h
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br X Desde esa exigencia de una correcta
2019-05-22

X. Desde esa exigencia de una correcta hermeneusis receptora, la mecánica expositiva del misterio procederá, sin embargo, complicando esa primera alegoría que ya es el sacramento en sí y levantando, Caspase-6 Colorimetric Assay Kit partir de la transposición o metáfora que diseña (Cristo como pa
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