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While most children with FSE do well Verity
2018-11-14
While most children with FSE do well (Verity et al., 1993; Shinnar et al., 2001), our findings in a rat model that mimics the clinical condition (Dube et al., 2006) raises the question of whether children who seemingly do well after febrile status epilepticus actually are spared injury or whether th
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In this issue of Proietti and colleagues analyzed pooled
2018-11-14
In this gingerol issue of , Proietti and colleagues () analyzed pooled datasets (n=3646) from SPORTIF III and V trials of warfarin-treated patients dependent on renal function. Diminished creatinine clearance (70%, whilst diabetes mellitus, aspirin use and RI were inversely associated with TTR>70%.
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Macrophages are now regarded as prominent players in metabol
2018-11-14
Macrophages are now regarded as prominent players in metabolic disorder and associated diseases. Their sub-populations (M1 and M2 macrophages) may have either deleterious or protective functions towards inflammatory regulation depending on certain conditions of various inflammatory microenvironments
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br Methods br Results br Discussion
2018-11-14
Methods Results Discussion Insufficiency of GCase activity in order baicalein due to GBA1 gene mutations is the molecular mechanism of GD. However, it has been observed that patients with the same GCase mutations may have significant variably in disease presentation, from a life-threatening
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SAR405 Conversely ECM accumulation in the liver is a hallmar
2018-11-14
Conversely, ECM accumulation in the liver is a hallmark of hepatic fibrosis and is associated with hepatic stellate cell activation due to inflammatory signaling (Bataller and Brenner, 2005). ECM reprogramming is necessary for adipose growth and expansion on energy dense diets, and fibrosis in fat t
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This latter study is particularly important in the
2018-11-14
This latter study is particularly important in the context of vaccine refusal, since it supports a growing body of research which underscores the role of clusters of non-vaccinators in lowering herd immunity and allowing for disease outbreaks (Salathé and Bonhoeffer, 2008; Liu et al., 2015). The US
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In contrast with hydrophilic metabolites the lipid
2018-11-14
In contrast with hydrophilic metabolites, the lipid profile was relatively uniform among samples and did not highlight their heterogeneity. The levels CEs with long-chain highly desaturated fatty acids were elevated in tumors; this was consistent with the notion that clear cell RCCs are rich in CEs
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For each of the rHSA samples
2018-11-14
For each of the rHSA samples, approximately 10µg were diluted in 50mM ammonium bicarbonate to a total volume of 200µl. To each solution 10µl of 250mM dithiothreitol (DTT) in 50mM NH4HCO3 were added followed by incubation for 1h at 60°C. Next, 20µl of 250mM iodoacetamide in 50mM NH4HCO3 were added an
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For the samples sintered from the nanometric micrometric pow
2018-11-14
For the samples sintered from the 40% nanometric – 60% micrometric powders, with both compaction procedures, the elastic limit is within the 500–530MPa range. The direct-SPS sample presents a sharper strain hardening, especially in the beginning of the plastic deformation, for a maximum stress of 73
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br Data The data presented in Table supports the research
2018-11-14
Data The data presented in Table 2 supports the research article “A rapid, highly sensitive and culture-free detection of pathogens from blood by positive enrichment” [1]. Table 1 shows a list of primers and probes used in the study [2–4]. These primers and probes have been used in qPCR experime
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To be able to recognize the ungrammatical
2018-11-14
To be able to recognize the ungrammatical use of newly-learned words, toddlers must have proceeded in two steps. First, they MG262 had to learn the syntactic category of the novel word (i.e. noun or verb) during the training session. Second, as toddlers had never heard the newly-learned words prece
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Caspase-1 Fluorometric Assay Kit Inter hemispheric differen
2018-11-13
Inter-hemispheric differences in power spectrum appeared during both monaural and binaural stimulation, suggesting a dependence on factors other than the stimulated side, e.g., hemispheric dominance or other processes that are happening simultaneously. Even though the major changes in power spectra
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Intercalating molecules such as metal complexes based on rut
2018-11-13
Intercalating molecules such as metal complexes based on ruthenium, osmium, iridium, platinum, cobalt [14–17] or organic compounds [18] may be a good method for electrochemical DNA probing because of their advantages such as reversibility of the redox reaction, chemical stability and simple function
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Recordings in PPN neurons using M NCS were
2018-11-13
Recordings in PPN neurons using 1μM NCS-1 were found to increase the amplitude and frequency of ramp-induced oscillations within ~25min of diffusion into the cell. Fig. 1 is a representative example of ramp-induced membrane potential oscillations in a PPN neuron in the presence of synaptic blockers
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Similarly the transmitted THz signal plotted in Fig b shows
2018-11-13
Similarly, the transmitted THz signal plotted in Fig. 4(b) shows a large and precipitous decrease upon application of each drop of DNA solution. But unlike the DC current, the THz signal recovers to its previous level and goes slightly higher upon drying. The decrease and recovery can be explained b
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